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Kaufen Nizagara Online

  • €0,73
  • Verfügbarkeit: Lagernd
  • Wirkstoff: sildenafil
Nizagara ist ein orales Arzneimittel zur Behandlung der männlichen Impotenz (zB erektile Dysfunktion) eingesetzt. Nizagara 's Vorteile sind eine große Sicherheit Track Record und praktisch keine Nebenwirkungen. Die Wirkung von Nizagara beginnt in 30 Minuten bis 1 Stunde und dauert etwa 4 Stunden.
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100 mg
Produktname Pro Pille Pro Packung  
10 pillen €3,14 €31,36
30 pillen €1,77 €94,08 €53,05
60 pillen €1,43 €188,16 €85,58
90 pillen €1,31 €282,24 €118,11
120 pillen €1,26 €376,32 €150,63
180 pillen €1,20 €564,48 €215,70
270 pillen €1,16 €846,72 €313,29
50 mg
Produktname Pro Pille Pro Packung  
10 pillen €2,64 €26,39
30 pillen €1,48 €79,17 €44,42
60 pillen €1,19 €158,33 €71,48
90 pillen €1,09 €237,50 €98,53
120 pillen €1,05 €316,67 €125,58
180 pillen €1,00 €475,00 €179,68
270 pillen €0,97 €712,51 €260,85
360 pillen €0,95 €950,01 €342,02
25 mg
Produktname Pro Pille Pro Packung  
30 pillen €1,96 €58,92
60 pillen €1,29 €117,83 €77,34
90 pillen €1,06 €176,75 €95,76
120 pillen €0,95 €235,66 €114,19
180 pillen €0,84 €353,49 €151,04
270 pillen €0,76 €530,24 €206,32
360 pillen €0,73 €706,98 €261,57

Nizagara

Drug Uses

Nizagara is used for treating erectile dysfunction (e.g. male impotence). It works by helping the blood flow into the penis to achieve and maintain an erection during sexual stimulation. 

How to use

Nizagara is to be taken 30 minutes to 1 hour before sexual activity. You may take it up to 4 hours before sexual activity. Nizagara is not supposed to be taken more often than once per day. 

Drug Class and Mechanism

Nizagara is a phosphodiesterase type 5 inhibitor and it works by helping the blood flow into the penis to achieve and maintain an erection during sexual stimulation.

Missed Dose

Nizagara is to be used as necessary, so you are not supposed to take it according to a schedule.

Storage

Nizagara is to be kept in its original container. It is to be stored at room temperature between 59 and 86 degrees F (15-30 degrees C) away from moisture, heat and light and out of the reach of children.

Warnings/Precautions

Do not take Nizagara, if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket), or recreational drugs such as amyl nitrate or nitrite ('poppers'). 

Before taking Nizagara, tell your doctor about all other medications you use for erectile dysfunction, or if you are using any of the following medications:
bosentan (Tracleer);
a blood thinner such as warfarin (Coumadin);
cimetidine (Tagamet, Tagamet HB);
an antibiotic such as erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxin);
doxazosin (Cardura), prazosin (Minipress), Terazosin (Hytrin);
HIV medicines such as amprenavir (Agenerase), tipranavir (Aptivus), darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune), indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), atazanavir (Reyataz), or nelfinavir (Viracept);
an antifungal medication such as itraconazole (Sporanox) or ketoconazole (Nizoral);
carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin); or
rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
Tell your doctor about all the prescriptions and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

If you have heart problems severe enough to make sexual activity a dangerous, you should avoid using Nizagara. Use it cautiously, if you've had a heart attack, stroke, or life-threatening heart irregularities within the past 6 months. Be equally cautious, if you have severe high or low blood pressure, heart failure or unstable angina.

In case of cardiac symptoms developing (for example, dizziness, nausea, and chest pain) during sexual activity, do not continue. Tell your doctor about the problem as soon as possible.

If you have a condition that might result in long-lasting erections, such as sickle cell anemia, multiple myeloma (a disease of the bone marrow), or leukemia, use Nizagara with caution. Also use cautiously if you have a genital problem or deformity such as Peyronie's disease. If an erection lasts more than 4 hours, seek treatment immediately. Permanent damage and impotence could result.

If you have a bleeding disorder, a stomach ulcer, or the inherited eye condition known as retinitis pigmentosa, use Nizagara with caution. Its safety under these circumstances has not been studied yet.

Possible Side Effects

If you experience any of the following serious side effects, stop taking Nizagara and seek emergency medical attention or notify your doctor immediately: 
sudden vision loss;
ringing in your ears, or sudden hearing loss;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
irregular heartbeat;
swelling in your hands, ankles, or feet;
shortness of breath;
vision changes;
feeling light-headed, fainting; or
penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
warmth or redness in your face, neck, or chest;
stuffy nose;
headache;
upset stomach; or
back pain.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

More Information

If you are older than 65 years, you can suffer Nizagara side effects. However, your physician may prescribe you a lower dose of this medication.

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Wenn man den Sicherheitsempfehlungen folgt und die Gegenanzeigen, Warnhinweise und Vorsichtsmaßnahmen berücksichtigt, reduziert sich das Risiko unerwünschter Reaktionen und Nebenwirkungen. Bei Patienten mit Überempfindlichkeit gegen Komponenten des Arzneimittels können jedoch die nachstehend aufgeführten leichten bis schweren nachteiligen Reaktionen auftreten. Wenden Sie sich an Ihren Arzt oder an einen Online-Facharzt, um das Risiko schwerwiegender Folgen auszuschließen. Suchen Sie die medizinische Hilfe sofort auf, wenn Sie folgende Nebenwirkungen bemerkt haben:

Rare

  • Abnormal vision
  • anxiety
  • behavior change similar to drunkenness
  • bleeding of the eye
  • blurred vision
  • bone pain
  • breast enlargement
  • chest pain
  • chills
  • cold sweats
  • confusion
  • convulsions (seizures)
  • cool and pale skin
  • deafness or hearing loss
  • decrease in amount of urine or the frequency of urination
  • decreased vision
  • difficulty in concentrating
  • dizziness or lightheadedness, especially when getting up suddenly from a lying or sitting position
  • double vision
  • drowsiness
  • dry eyes
  • dry mouth
  • dryness, redness, scaling, or peeling of the skin
  • excessive hunger
  • eye pain
  • fainting or faintness
  • fast, irregular, or pounding heartbeat
  • feeling of something in the eye
  • fever or chills
  • headache (severe or continuing)
  • increase in the size of the pupil
  • increased sweating
  • increased thirst
  • lower back or side pain
  • migraine headache
  • nausea (severe or continuing)
  • nervousness
  • nightmares
  • numbness of the hands
  • painful, swollen joints
  • prolonged, painful erection of penis
  • redness, burning, or swelling of the eyes
  • redness, itching, or tearing of the eyes
  • restless sleep
  • seeing shades of colors differently than before
  • sensitivity to light
  • shakiness
  • skin lesions with swelling
  • skin paleness
  • skin rash, hives, or itching
  • skin ulcers
  • slurred speech
  • sore throat
  • sudden weakness
  • swelling of the face, hands, feet, or lower legs
  • trouble breathing
  • twitching of the muscles
  • unusual feeling of burning or stinging of the skin
  • unusual tiredness or weakness
  • vision changes
  • vision loss, temporary
  • Abdominal or stomach pain
  • abnormal dreams
  • anxiety
  • clumsiness or unsteadiness
  • cough
  • diarrhea or stomach cramps (severe or continuing)
  • difficulty in swallowing
  • ear pain
  • increased amount of saliva
  • increased skin sensitivity
  • lack of coordination
  • loss of bladder control
  • mental depression
  • nausea
  • numbness or tingling of the hands, legs, or feet
  • rectal bleeding
  • redness or irritation of the tongue
  • redness, soreness, swelling, or bleeding of the gums
  • ringing or buzzing in the ears
  • sensation of motion, usually whirling, either of one's self or of one's surroundings
  • sexual problems in men (continuing), including failure to experience a sexual orgasm
  • sleepiness
  • sores in the mouth and on the lips
  • tense muscles
  • trembling and shaking
  • vomiting
  • waking to urinate at night
  • worsening of asthma

More Common

  • Aches or pains in the muscles
  • bloody nose
  • diarrhea
  • difficult or labored breathing
  • flushing
  • headache
  • pain or tenderness around the eyes and cheekbones
  • redness of the skin
  • sneezing
  • stomach discomfort following meals
  • stuffy or runny nose
  • trouble sleeping
  • unusually warm skin

Less Common

  • Bladder pain
  • burning feeling in the chest or stomach
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • cloudy or bloody urine
  • dizziness
  • increased frequency of urination
  • indigestion
  • pain on urination
  • stomach upset
  • tenderness in the stomach area

Incidence Not Known

  • Blindness
Type Small Molecule
Accession Number DB00203  (APRD00556)
Groups Approved, Investigational
Synonyms
  • 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
UNII 3M7OB98Y7H
CAS number 139755-83-2
Weight Average: 474.576
Monoisotopic: 474.204924168
Chemical Formula C22H30N6O4S
InChI
InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
IUPAC Name
5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin-7-one
Protein binding

96%

Toxicity Not Available
Half life

4 hours

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